Novel triterpene sulfates from Fusarium compactum using a rhinovirus 3C protease inhibitor screen.
نویسندگان
چکیده
Two novel triterpene sulfates have been isolated from Fusarium compactum by bioactivity-directed fractionation using an assay which measures the inhibition of proteolytic activity of rhinovirus 3C protease on a fluorogenic peptide substrate. The compounds were purified by countercurrent and reverse phase chromatographies. NMR, MS, UV and IR studies revealed two triterpene sulfates, uncommon metabolites of terrestrial fungi.
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 49 6 شماره
صفحات -
تاریخ انتشار 1996